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Update on prevention and treatment of Helicobacter pylori infection

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Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 16

DOI:: 10.11569/wcjd.v24.i16.2454

Key Word:: 幽门螺旋杆菌;致病性;治疗方案选择;保护作用;预防;Helicobacter pylori;Pathogenicity;Treatment options;Protective effect;Prevention

Abstract：从1983年Marshall和Warren首次从胃黏膜中分离出幽门螺旋杆菌(Helicobacter pylori,H.pylori)以来,迄今已走过了33个年头,现已确定H.pylori不仅仅与慢性胃病密切相关,且与多个系统疾病相关.随着对H.pylori感染广泛深入的研究,对H.pylori致病性的认识、防治方法上均有显著的提高.2015年邹全明教授团队重组H.pylori口服疫苗的开发,为预防H.pylori感染显示出广阔的前景.2014年日本旨在通过全人群根除H.pylori感染降低胃癌发病的计划,引起广泛的关注.H.pylori感染是一种传染病,我国人群感染率约56％,因此,加强H.pylori细菌学和发病机制的研究,做好其防治,寻求抗菌疗效高、耐药性低的治疗方案、提高感染患者的可及性是一项任重而道远的艰巨任务.

Reference

[1]中华医学会消化病学分会幽门螺杆菌学组/全国幽门螺杆��.第四次全国幽门螺杆菌感染处理共识报告[J].2012,(10).
[2]Department of Respiratory Therapy,China Medical University Hospital,Taichung Taiwan,Department of Respiratory Therapy,etc.Increased risk of chronic obstructive pulmonary disease among patients withHelicobacter pyloriinfection: a population-based cohort study[J].2015.
[3]Tiziana, Larussa,Isabella, Leone,Evelina, Suraci,etc.Helicobacter pylori and T Helper Cells: Mechanisms of Immune Escape and Tolerance.[J].2015,2015.
[4]Fock,K.M.,Graham,D.Y.,Malfertheiner,P..Helicobacter pylori research: Historical insights and future directions[J].2013,10(8).
[5]Yi-Jian, Ding,Tian-Lian, Yan,Xin-Lan, Hu,etc.Association of Salivary Helicobacter pylori Infection with Oral Diseases: a Cross-sectional Study in a Chinese Population.[J].2015,12(9).
[6]Jin-Eung Kim,Min-Soo Kim,Yeo-Sang Yoon,etc.Use of selected lactic acid bacteria in the eradication of Helicobacter pylori infection[J].2014,52(11).
[7]Leonardo H. Eusebi,Rocco M. Zagari,Franco Bazzoli.Epidemiology of Helicobacter pylori Infection[J].2014,19(s1).
[8]Malfertheiner P,Chan FK,McColl KE.Peptic ulcer disease.[J].2009,374(9699).
[9]Sung Eun, Kim,Moo In, Park,Seun Ja, Park,etc.Trends in Helicobacter pylori eradication rates by first-line triple therapy and related factors in eradication therapy.[J].2015,30.
[10]Chen, JS,Li, N,She, FF.Helicobacter pylori outer inflammatory protein DNA vaccine-loaded bacterial ghost enhances immune protective efficacy in C57BL/6 mice[J].2014,32(46).
[11]Pan, Xing,Wang, Bao-ning,Shi, Xin-li,etc.Protection against Helicobacter pylori infection in BALB/c mice by oral administration of multi-epitope vaccine of CTB-UreI-UreB[J].2015,73(5).
[12]Baoning, Wang,Xing, Pan,Hongren, Wang,etc.Immunological response of recombinant H. pylori multi-epitope vaccine with different vaccination strategies.[J].2014,7(10).
[13]Ping-I Hsu,Pei-Chin Lin,David Y Graham.Hybrid therapy for Helicobacter pylori infection:A systemic review and meta-analysis[J].2015,(45).
[14]Soo Hyun, Jang,Hyejin, Lee,Jun Suk, Kim,etc.Association between Helicobacter pylori Infection and Cerebral Small Vessel Disease.[J].2015,36(5).
[15]Huang, Yan,Zhan, Xue.Sequential Therapy is Superior to Triple Therapy for Helicobacter pylori Infection in Children: A Meta-Analysis[J].2016,83(4).
[16]Abdolrahim, Masjedizadeh,Narjes, Zaeemzadeh,Seyyed Ali, Mard,etc.Comparing the efficacy of four different protocols for eradicating of Helicobacter pylori infection in Ahvaz, southwest Iran.[J].2015,10(2).
[17]主编池肇春 ... [等].幽门螺杆菌感染及其相关疾病的诊断与治疗[M].1900.
[18]J.-M. Liou,C.-C. Chen,Y.-C. Lee,etc.Systematic review with meta-analysis: 10- or 14-day sequential therapy vs. 14-day triple therapy in the first line treatment of Helicobacter pylori infection[J].2016,(4).
[19]Sugano, Kentaro,Tack, Jan,Kuipers, Ernst J.,etc.Kyoto global consensus report on Helicobacter pylori gastritis[J].2015,64(9).
[20]Georgopoulos, Sotirios D.,Papastergiou, Vasilios,Karatapanis, Stylianos.Treatment of Helicobacter Pylori infection: optimization strategies in a high resistance era[J].2015,16(15).
[21]Charles C, King,Marygorret, Obonyo.Helicobacter pylori modulates host cell survival regulation through the serine-threonine kinase, 3-phosphoinositide dependent kinase 1 (PDK-1).[J].2015,15.
[22]Apostolopoulos, Periklis,Koumoutsos, Ioannis,Ekmektzoglou, Konstantinos,etc.Concomitant versus sequential therapy for the treatment of Helicobacter pylori infection: a Greek randomized prospective study[J].2016,51(2).
[23]Malfertheiner,P.,Megraud,F.,O'Morain,C.A.,etc.Management of Helicobacter pylori infection - The Maastricht IV/ Florence consensus report[J].2012,61(5).
[24]Qiao, Yu,Shenghong, Zhang,Li, Li,etc.Enterohepatic Helicobacter Species as a Potential Causative Factor in Inflammatory Bowel Disease: A Meta-Analysis.[J].2015,94.
[25]Oh, Bumjo,Kim, Bong-Soo,Kim, Ji Won,etc.The Effect of Probiotics on Gut Microbiota during the Helicobacter pylori Eradication: Randomized Controlled Trial[J].2016,21(3).
[26]Sung Noh Hong,Seung Min Lee,Jeong Han Kim,etc.Helicobacter pylori infection increases the risk of colorectal adenomas: cross-sectional study and meta-analysis.[J].2012,57(8).
[27]Xi, Zheng,Lin, Lyu,Zhechuan, Mei.Lactobacillus-containing probiotic supplementation increases Helicobacter pylori eradication rate: evidence from a meta-analysis.[J].2013,105(8).
[28]Tyler J Caron,Kathleen E Scott,James G Fox,etc.Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier[J].2015,(40).
[29]Yi, Gong,Yan, Li,Qian, Sun.Probiotics improve efficacy and tolerability of triple therapy to eradicate Helicobacter pylori: a meta-analysis of randomized controlled trials.[J].2015,8(4).
[30]Genta, Robert M.,Sonnenberg, Amnon.Helicobacter pylori is a Risk Factor for Colonic Neoplasms[J].2013,108(2).
[31]Angelo, Zullo,Lorenzo, Ridola,Vincenzo De, Francesco,etc.High-dose esomeprazole and amoxicillin dual therapy for first-line Helicobacter pylori eradication: a proof of concept study.[J].1900,28(4).
[32]Mohamed Alboraie,Motaz Saad,Jaber Al-Ali,etc.Quadruple therapy versus standard triple therapy for eradication of Helicobacter pylori in Kuwait[J].2015,16(3-4).
[33]Javier P, Gisbert.[Helicobacter pylori-associated diseases].[J].2015,38 Suppl 1.
[34]Lin M,Lin L,She F,etc.Therapeutic vaccination with Salmonella-delivered codon-optimized outer inflammatory protein DNA vaccine enhances protection in Helicobacter pylori infected mice.[J].2012,30(36).
[35]Mehdi, Alimadadi,Mohammadreza, Seyyedmajidi,Saeid, Amirkhanlou,etc.Impact of Creatinine Clearance on Helicobacter Pylori Eradication Rate in Patients With Peptic Ulcer Disease.[J].2015,9(6).
[36]Ismail Hakki Kalkan,Ferdane Sapmaz,Sefa Güliter,etc.Severe gastritis decreases success rate of Helicobacter pylori eradication[J].2016,(9).
[37]Yoshio, Yamaoka.Increasing evidence of the role of Helicobacter pylori SabA in the pathogenesis of gastroduodenal disease.[J].2008,2(3).
[38]M Y Sun,S L Shi,Z S Lv,etc.Helicobacter pylori infection and normal colorectal mucosa-adenomatous polyp-adenocarcinoma sequence: a meta-analysis of 27 case-control studies.[J].2014,16(4).
[39]Yamaoka Y,Graham DY,Lu H.Helicobacter pylori virulence factors: facts and fantasies.[J].2005,21(6).
[40]Toller, I.M.,Neelsen, K.J.,Steger, M.,etc.Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells[J].2011,108(36).
[41]Rong Zhu,Kan CHEN,Yuan-Yuan Zheng,etc.Meta-analysis of the efficacy of probiotics in Helicobacter pylori eradication therapy[J].2014,(47).
[42]X, Bai,D, Wang,Z, Fan,etc.Helicobacter pylori may cause otitis media with effusion: a pilot study.[J].2012,8(4).