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Clinical effects of double routes of administration of rhubarb in treatment of acute pancreatitis

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Author:
No author available
Journal Title:
World Chinese Journal of Digestology
Issue:
4
DOI:
10.11569/wcjd.v24.i4.607
Key Word:
大黄;双途径治疗;急性胰腺炎;Rhubarb;Double routes of administration;Acute pancreatitis

Abstract´╝Ü 目的:观察大黄鼻饲灌肠联合治疗急性胰腺炎(acute pancreatitis,AP)的疗效.方法:将83例AP患者随机分为常规治疗组,大黄双途径+常规治疗组、大黄鼻饲+常规治疗组.观察3组患者住院费用、住院时间、肠道功能恢复时间、Ranson评分、CT分级,检测血浆降钙素原(plasma calcitonin,PCT)、C反应蛋白(C-reactive protein,CRP),并进行比较.结果:3组患者无1例死亡,大黄双途径+常规治疗组患者的肠道功能恢复时间、平均住院天数和住院费用均低于其他两组(与常规治疗组比,P<0.05;与大黄鼻饲+常规治疗组比,P<0.05).治疗1 wk后,CT分级、CRP、PCT明显下降(P<0.05).结论:大黄双途径联合治疗AP,能促进患者肠道功能恢复,降低炎症反应,缩短住院时间,减少医疗费用,改善预后.

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