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Advances in understanding the pathogenesis of irritable bowel syndrome
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 32
- DOI:
- 10.3969/j.issn.1009-3079.2009.32.008
- Key Word:
- 肠易激综合征;病理生理学;病因学
Abstract： 肠易激综合征(irritable bowel syndrome,IBS)是一种以腹部不适和排便习惯改变为特征的胃肠功能性疾病.IBS的发病机制仍不清楚,传统观点认为基因、心理社会因素、胃肠动力障碍和内脏高敏感性等是引起IBS的关键因素.近年来,人们陆续发现了一些与IBS发病相关的新病理生理学改变依据,如脑肠轴调节失常、肠道感染、肥大细胞的激活并释放活性物质等.本文总结与IBS发病机制相关的一些最新研究进展.
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