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Feasibility of using 18F-FDG PET/CT for pretherapeutic evaluation of advanced gastric cancer

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Author:
No author available
Journal Title:
WORLD CHINESE JOURNAL OF DIGESTOLOGY
Issue:
21
DOI:
10.3969/j.issn.1009-3079.2009.21.008
Key Word:
进展期胃癌;18氟-氟脱氧葡萄糖-正电子发射断层显像;治疗前评估

Abstract´╝Ü 目的:探讨18F-FDG PET/C对进展期胃癌治疗前评估的可行性.方法:回顾性分析40例进展期胃癌患者18F-FDG PET/CT常规检查结果资料,与内镜、手术病理和临床随访作对照;其中14例患者行根治性手术,余行化疗或姑息治疗.根据解剖部位将淋巴结分为N1+N2和N3组,淋巴结有无转移以组为单位.原发灶、淋巴结及其他器官转移灶的判断通过目测分析结合标准化摄取值来确定.结果:PET/CT对胃原发癌的灵敏度为97.5%.PET和CT的灵敏度分别为65%和90%;14例根治手术患者N1、N2淋巴结有无转移PET/CT的确诊率为85.7%,灵敏度为71.4%,特异性为77.8%;对N3淋巴结的灵敏度为100%.PET/CT发现21处临床未怀疑的转移灶:PET/CT检查后40%(16/40)的病例分期发生变化.结论:18F-FDG PET/CT可用于进展期胃癌的治疗前评估.

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