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Therapeutic effect of cinnamon oil on gastric candida albicans infection in mice

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Author:
No author available
Journal Title:
WORLD CHINESE JOURNAL OF DIGESTOLOGY
Issue:
15
DOI:
10.3969/j.issn.1009-3079.2009.15.013
Key Word:
肉桂油;小鼠;胃;白念珠菌

Abstract´╝Ü 目的: 探讨肉桂油治疗胃白念珠菌感染的可行性.方法: 制作胃白念珠菌感染小鼠120只, 随机分为4组, 每组30只. 肉桂油治疗组分3组, 每天给予1 mL 1.25、1.88、2.5 g/L肉桂油溶液灌胃, 对照组每天给予50 g/L葡萄糖溶液1 mL灌胃, 10 d后取小鼠胃组织行真菌镜检及组织病理检查, 发现白念珠菌菌丝为阳性.结果: 3个浓度的肉桂油治疗组的真菌镜检及组织病理检查阳性率均显著低于对照组(χ2 = 14.14, 6.97, 7.04;30.08, 25.36, 28.09, 均P<0.01), 肉桂油治疗组之间比较无差异(χ2 =2.04, 0.28, P>0.05).结论: 三种浓度肉桂油均可杀死小鼠胃内的白念珠菌, 肉桂油可用来治疗胃白念珠菌感染.

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