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Research progress in the relationship between p53 gene network and H pylori-induced gastric diseases

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 7

DOI:: 10.3969/j.issn.1009-3079.2009.07.010

Key Word:: p53;幽门螺杆菌;胃疾病

Abstract： H pylori与胃黏膜病变关系密切已被公认,H pylori感染可引起胃黏膜细胞增殖与凋亡的失衡,这与其致病致癌密切相关.p53基因这一复杂的网络系统在调控细胞凋亡与增殖的过程中,发挥重要的作用.就p53下游基因网络与H pylori、胃黏膜细胞增殖凋亡之间的关系作一综述.

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