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Alteration of glycan structure in liver cancer

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 36

DOI:: 10.3969/j.issn.1009-3079.2008.36.009

Key Word:: 糖基化;聚糖结构;癌症;肝癌

Abstract：蛋白质糖基化是一种常见的翻译后修饰,几乎50%的蛋白质都被认为具有糖基化修饰.糖基化作用产生大量聚糖,其结构变化与许多生理和病理过程相关,恶性肿瘤的发生侵袭就是其中之一.本文对糖蛋白聚糖的结构和功能进行描述,并且举例说明与肝癌相关的某些糖蛋白聚糖结构的变化.

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