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Multisection spiral CT perfusion for patients with acute pancreatitis
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 35
- DOI:
- 10.3969/j.issn.1009-3079.2008.35.006
- Key Word:
- 胰腺炎;X线计算机体层摄影术;灌注
Abstract： 目的:应用多层螺旋CT探讨急性胰腺炎(acute pancreatitis,AP)患者胰腺CT灌注的变化以及CT灌注参数与急性胰腺炎临床常用病情指标的关系,以探讨CT灌注成像在急性胰腺炎中的临床应用价值.方法:2006-08/2008-01 急性胰腺炎患者82例,入院后2-3 d采用德国Siemens somatom Sensation 64层螺旋CT进行动态增强扫描,其中5例因患者移动等致胰腺CT灌注成像失败.30例对照组,其中3例健康志愿者,27例因其他疾病行腹部CT检查患者.利用螺旋CT自带软件PCT进行处理得到灌注参数:BF(血流量)、BV(血容量)、TTP(峰值时间)、PS(表面通透性)等.结果:急性胰腺炎组BF、BV较正常对照组相比下降明显(110.57±60.04 VS 133.55±25.70,156.68±65.11 VS 193.78±27.01,均P＜0.05),TTP、PS变化无统计学意义.重型急性胰腺炎与轻型急性胰腺炎相比,住院时间延长(11.51±8.46 d VS 20.91±8.40 d,P＜0.05),而腹痛缓解时间离散度大,虽有延长趋势,但无统计学意义.急性胰腺炎CT灌注参数BF、BV与腹痛缓解时间、住院总时间、局部并发症间存在相关关系(P＜0.05).结论:急性胰腺炎患者胰腺血流灌注降低,灌注参数Bv、BF与AP临床常用病情指标存在相关关系,CT灌注成像在AP病情评估中具有临床应用价值.
- [1]中华医学会消化病学分会胰腺疾病学组.中国急性胰腺炎诊治指南（草案）[J].2004,(3).
- [2]王欣,徐荣天,卢涛,等.急性胰腺炎的多层螺旋CT灌注成像研究[J].2006,(1).
- [3]李震,胡道予,肖明,等.轻症急性胰腺炎多层螺旋CT灌注成像[J].2006,(5).
- [4]王琦,徐荣天,王欣,等.急性胰腺炎多层螺旋CT灌注成像的初步研究[J].2006,(2).
- [5]Vardas E,Chatzicostas C,Romanos J,etc.Balthazar Computed Tomography Severity Index Is Superior to Ranson Criteria and APACHE II and III Scoring Systems in Predicting Acute Pancreatitis Outcome.[J].2003,36(3).
- [6]L, Axel.Cerebral blood flow determination by rapid-sequence computed tomography: theoretical analysis.[J].1980,137.
- [7]Yazumi S,Tsuji Y,Chiba T,etc.Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis.[J].2007,5(12).
- [8]A K Banerjee,R J Steele.Current views on the pathophysiology of acute biliary pancreatitis.[J].1995,36(6).
- [9]P, Malfertheiner,T P, Kemmer.Clinical picture and diagnosis of acute pancreatitis.[J].1991,38.