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Research progress in the relationship between HO-CO pathway and haemodynamic variation of cirrhotic portal hypertension

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 8

DOI:: 10.3969/j.issn.1009-3079.2008.08.014

Key Word:: HO-CO系统;肝硬化;门静脉高压

Abstract：肝硬化门脉高压患者多存在高动力循环状态,有报道血红素氧合酶(hemeoxygenase,HO)与内源性一氧化碳(carbon monoxide,CO)作为HO-CO系统在血管调节中发挥重要的生物学效应,与肝硬化门静脉高压(portal hypertension,PH)的持续存在、肝微循环变化以及高动力循环状态有着密切的关系.本文将从肝硬化PH的血液动力学改变、HO-CO系统的生物学活性和HO-CO系统与PH的血液动力学改变等三部分的研究进展作一综述.

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