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Inducing peripheral blood cells for a decrease in decompensated cirrhosis

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Author:
No author available
Journal Title:
WORLD CHINESE JOURNAL OF DIGESTOLOGY
Issue:
27
DOI:
10.3969/j.issn.1009-3079.2007.27.001
Key Word:
肝硬化;脾功能亢进;造血干细胞;免疫反应

Abstract´╝Ü 肝硬化失代偿期并发的脾功能亢进和血细胞减少,互为因素,相互影响,是造成病情进展的重要原因.部分患者脾脏切除后,外周血细胞不仅无增加,反而出现进行性下降的表现,表明在肝硬化时外周血细胞减少,除了脾脏及病毒因素外也存有其他因素参与这一病程.各种免疫细胞因子变化、造血干细胞的状态都可能参与和调节肝硬化失代偿期外周血细胞减少这一过程,阐释肝硬化失代偿期外周血细胞减少成因机制对治疗意义重大,值得深入研究.

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