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Epigenetic modification and gastrointestinal tumor
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 34
- DOI:
- 10.3969/j.issn.1009-3079.2006.34.001
- Key Word:
- 胃肠道肿瘤;基因调控;DNA甲基化;组蛋白修饰
Abstract： 肿瘤的形成受遗传学和表遗传学修饰的影响.近年来,越来越多的证据表明,表遗传学修饰在肿瘤进展中同样有重要作用,表遗传调控可以影响基因转录活性而不涉及DNA序列的改变.胃肠道肿瘤是我国最常见的肿瘤,表遗传研究对了解胃肠道肿瘤的的发病机制、细胞免疫与防御、细胞分化以及预防治疗等方面具有十分重要的意义.
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