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Methodology and significance of detection for hepatitis B virus covalently closed circular DNA
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 20
- DOI:
- 10.3969/j.issn.1009-3079.2006.20.010
- Key Word:
- 肝炎病毒;乙型;共价闭合环状DNA;聚合酶链反应
Abstract： HBV cccDNA是HBV mRNA和前基因组RNA的合成模板,是HBV持续感染的关键因素,检测HBV cccDNA对进一步认识HBV生活周期及指导抗病毒治疗等有重要意义.最近,利用PCR方法检测HBV cccDNA受到越来越多的重视,现就检测HBV cccDNA的各种PCR方法及其研究意义进行综述.
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