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Methodology and significance of detection for hepatitis B virus covalently closed circular DNA

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Author:
No author available
Journal Title:
WORLD CHINESE JOURNAL OF DIGESTOLOGY
Issue:
20
DOI:
10.3969/j.issn.1009-3079.2006.20.010
Key Word:
肝炎病毒;乙型;共价闭合环状DNA;聚合酶链反应

Abstract´╝Ü HBV cccDNA是HBV mRNA和前基因组RNA的合成模板,是HBV持续感染的关键因素,检测HBV cccDNA对进一步认识HBV生活周期及指导抗病毒治疗等有重要意义.最近,利用PCR方法检测HBV cccDNA受到越来越多的重视,现就检测HBV cccDNA的各种PCR方法及其研究意义进行综述.

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