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Current status of interleukin-10 in treatment of acute pancreatitis

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 1

DOI:: 10.3969/j.issn.1009-3079.2005.01.015

Key Word:: No keyword available

Abstract：急性胰腺炎(acute pancreatitis)是临床常见的外科急腹症,其病情凶险、并发症多.近年来,虽然急性胰腺炎的治疗取得了长足的进步,但其死亡率仍高达22.7%.随着对急性胰腺炎发病机制不断的深入研究,抗炎细胞因子在阻断其病程演进中所起的重要作用日益受到关注.白介素10是急性胰腺炎时的强效抗炎细胞因子,在维持细胞因子网络平衡、抑制NF-κB的活化、改善胰腺相关性微循环障碍、抑制胰腺腺泡细胞凋亡、阻止胰腺持续缺血、坏死中起到了关键作用,有利于炎症的恢复.本文就白介素10在急性胰腺炎中的应用现状做一综述.

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