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核因子κB的信号转导机制及研究策略
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 4
- DOI:
- 10.3969/j.issn.1009-3079.2004.04.048
- Key Word:
- No keyword available
Abstract： @@ 核因子кB(nuclear factor of кB,NF-кB)是一种广泛存在的转录因子,几乎每个真核细胞中都存在NF-κB,不同的刺激信号激活该转录因子后,参与相应的基因表达的调控,如细胞的生长、分化、凋亡、炎症反应、肿瘤发生等[1-2].由于其广泛的生物学活性,对NF-кB的研究为阐明某些疾病的发病机制及治疗具有重要的意义.
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