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ERK信号传导通路与肝星状细胞周期调控

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 7

DOI:: 10.3969/j.issn.1009-3079.2003.07.042

Key Word:: No keyword available

Abstract：慢性肝病的重要病理基础是肝纤维化,慢性肝病通过纤维化的发展走向肝硬化现公认肝星状细胞(HSC)的活化与增生是肝纤维化进展的中心环节,HSC的增生有赖于一系列细胞内信息分子的调控,近年研究证实了ERK信号传导通路通过调控细胞周期相关周期蛋白的表达而调控细胞增生.因此本文对ERK信号传导通路调控HSC周期的研究概况作一扼要综述.

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