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The significance of pancreaticojejunostomy method on prevention of pancreatic leakage

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Author:
No author available
Journal Title:
WORLD CHINESE JOURNAL OF DIGESTOLOGY
Issue:
5
DOI:
10.3969/j.issn.1009-3079.2003.05.023
Key Word:
No keyword available

Abstract´╝Ü @@ 0引言自1935年Whipple发明胰十二指肠切除术(pancreatico-duodenectomy,PD)以来,胰肠吻合口漏一直是最常见、最严重的并发症,其危害性主要在于被胆肠液激活的胰酶漏入腹腔,腐蚀和消化周围组织,引起致命性大出血、肠漏和不易控制的腹腔感染等,最终造成患者死亡.文献报道PD后胰肠吻合口漏的发生率在5-25%,与之有关的死亡率达到20-50%.据美国最有代表性的2个胰腺外科中心约翰霍普金斯医院(johns hopkins)和麻省总院(massachuseus general hospital)最近的大宗病例报告,胰肠吻合口漏的发生率分别为14%和9.2%.

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