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Liver fibrosis and TNF-α, IL-6 and IL-10

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 7

DOI:: 10.3969/j.issn.1009-3079.2001.07.025

Key Word:: 肝硬化/病理生理学;肿瘤坏死因子;白细胞介素6;白细胞介素10

Abstract： @@肝纤维化(LF)是各种原因引起的慢性肝损伤所共有的细胞病理过程,其特征为大量细胞外基质(ECM)在Disse间隙沉积[1-5].近来,由于细胞生物学及细胞因子信号传导研究领域中取得的重大进展,越来越多的证据表明,肝纤维化是可以逆转的[6-10].各种细胞因子通过复杂的调节机制在肝纤维化的进展中起重要作用[11-15],从而使对细胞因子和肝纤维化的研究成为热点之一.

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