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Hp and gastroesophageal reflux disease

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 6

DOI:: 10.3969/j.issn.1009-3079.2001.06.021

Key Word:: 螺杆菌,幽门/致病力;螺杆菌感染/并发症;胃食管反流/病因学;胃食管反流/治疗

Abstract： @@ 胃食管反流病(gastroesophgeal reflux disease,GERD)是胃、十二指肠内容物反流入食管引起的胸骨后烧灼感、疼痛等症状及组织损害[1,2],常伴食管炎,是一种常见的胃肠动力障碍性疾病,在上消化道疾病中占较大比例[3-5].迄今其病因、发病机制尚未完全明确.研究证实,幽门螺杆菌(Helicobacter pylori,Hp)是慢性胃炎、胃十二指肠溃疡的主要致病因子[6-8],且与胃癌[6,7,9]、胃粘膜相关淋巴组织(mucosa assotiated lymphoid tissue,MALT)淋巴瘤密切相关[6,7,10].但Hp与GERD的关系尚存在较大争议[11-13].现就Hp与GERD的关系作一综述.

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