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胃幽门螺杆菌亚硝酸盐还原酶及亚硝胺合成酶活性的测定意义
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 1
- DOI:
- 10.3969/j.issn.1009-3079.2000.01.041
- Key Word:
- 螺杆菌,幽门;亚硝酸盐还原酶;亚硝胺合成酶;胃肿瘤
Abstract： @@ 幽门螺杆菌(Hp)与胃癌的关系日益受到广泛关注.大量的流行病学研究发现Hp感染高发区的胃癌发病率显著高于Hp感染低发区;血清Hp特异性抗体阳性率胃癌患者显著高于非胃癌患者.因而WHO已将Hp列为Ⅰ类致癌物.然其致癌机制迄今尚未阐明[1,2].亚硝酸盐,N-亚硝胺(简称亚硝胺)均属强烈致癌物,特别是后者已广泛用于实验动物胃癌模型的建立.
- [1]M ECraanen,WDekker,PBlok,etc.Intestinal metaplasia and Helicobacter pylori: an endoscopic bioptic study of the gastric antrum.[J].1992,33(1).
- [2]江希明等主编.肿瘤生物学[M].1990.