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Imiquimod-induced localized vitiligo-like hypopigmentation
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- Author:
- No author available
- Journal Title:
- International Journal of Dermatology and Venereology
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.2096-5540.2018.03.013
- Key Word:
- No keyword available
Abstract： Introduction Imiquimod is an immune response modifier,currently the 5％ imiquimod cream is approved for treatment of extemal genital,perianal warts,superficial basal cell carcinoma,and actinic keratoses.Its anti-viral activity and anti-tumoral activity seem to be dependent on focal activation of the immune system with induction,synthesis,and release of cytokines,such as interferonalpha,interleukin-12 and tumor necrosis factor alpha[1-2].
- [1]WANG Hong-wei,Miao Fei,SHI Lei,etc.Imiquimod-induced localized vitiligo in wife and lichen planus in husband[J].2013,(13).
- [2]Schofer H,Van-Ophoven A,Henke U,etc.Randomized, comparative trial on the sustained efficacy of topical imiquimod 5; cream versus conventional ablative methods in external anogenital warts.[J].2006,16(6).
- [3]SERRA, Maíra Chiarelli,MENICANTI, Claudia,PENNACCHIOLI, Elisabetta,etc.Vulvar vitiligo-like depigmentation and multiple halos of hypomelanosis at the trunk following treatment with imiquimod 5% cream for vulvar condylomata: casual or related events?.[J].2014,89(5).
- [4]J. Mashiah,S. Brenner.Possible mechanisms in the induction of vitiligo‐like hypopigmentation by topical imiquimod[J].2008,33(1).
- [5].Genital Vitiligo-like Hypopigmentation After Treatment With 5% Imiquimod[J].2017,108(4).
- [6]Yu CF,Peng WM,Oldenburg.Human plasmacytoid dendritic cells support Th17 cell effector function in response to TLR7 ligation.[J].2010,184(3).
- [7]Mori, S.,Akasaka, T..Imiquimod-induced vitiligo-like hypopigmentation after treatment for radiation keratosis[J].2016,41(8).
- [8]Drewniok C,Wienrich BG,Eberle J,etc.Death receptor-independent apoptosis in malignant melanoma induced by the small-molecule immune response modifier imiquimod.[J].2004,122(5).
- [9]Fu-Quan Long,Li-Shi Zhao,Yi-Hong Qian.Vitiligo or Vitiligo-like Hypopigmentation Associated with Imiquimod Treatment of Condyloma Acuminatum: Not a Casual Event[J].2017,130(4).
- [10]Wenfei, Li,Hongyan, Xin,Lingzhi, Ge,etc.Induction of vitiligo after imiquimod treatment of condylomata acuminata.[J].2014,14.
- [11]Oiso, Naoki,Narita, Tomohiko,Kawada, Akira.Imiquimod-induced vitiligo-like depigmentation over multiple solar keratosis in a patient with vitiligo[J].2017,27(1).
- [12]Pyun JH,Kim CH,Kang SU,etc.Imiquimod induces apoptosis of human melanocytes.[J].2010,302(4).
- [13]Tamu Brown,Monib Zirvi,George Cotsarelis,etc.Vitiligo-like hypopigmentation associated with imiquimod treatment of genital warts[J].2005,52(4).