Risk analysis of diabetes mellitus in patients with hidradenitis suppurativa: a meta-analysis
- Author:
- No author available
- Journal Title:
- International Journal of Dermatology and Venereology
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.2096-5540.2018.02.005
- Key Word:
- Hidradenitis suppurativa;Diabetes mellitus;Meta-analysis
Abstract： Objective The results of association studies between hidradenitis suppurativa and diabetes mellitus remain controversial.This study aimed to investigate the association between hidradenitis suppurativa and diabetes mellitus by reviewing all the available evidences comprehensively.Methods We performed a meta-analysis on observational studies that reported the odds ratio (OR) comparing diabetes mellitus risk in patients with hidradenitis suppurativa versus participants without hidradenitis suppurativa.Pooled OR and 95％ confidence intervals (95％CIs) were calculated using a random effect,generic inverse variance methods of DerSimonian and Laird.Results Four studies (two cross-sectional studies and two case-control studies) including 5,362 patients with hidradenitis suppurativa and 23,193participants without hidradenitis suppurativa were identified and coved in the meta-analysis.The pooled OR of diabetes mellitus in patients with hidradenitis suppurativa was 1.95 (95％CI:1.31-2.91).The statistical heterogeneity of this meta-analysis was I2 =63％.Conclusions This meta-analysis shows a signi ficant risk increase of diabetes mellitus incidence among patients with hidradenitis suppurativa.Patients with hidradenitis suppurativa should be regularly screened for diabetes mellitus as complication.
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