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Application of botulinum toxin type A in several skin diseases

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Author:
No author available
Journal Title:
International Journal of Dermatology and Venereology
Issue:
3
DOI:
10.3760/cma.j.issn.1673-4173.2016.03.017
Key Word:
肉毒杆菌毒素类,A型;多汗症;神经痛,带状疱疹后;瘢痕疙瘩;皮肤衰老;Botulinum toxins,type A;Hyperhidrosis;Neuralgia,postherpetic;Keloid;Skin aging

Abstract: With further insights into action mechanisms of botulinum toxin type A,it has been applied more and more widely in dermatology.Botulinum toxin type A can be used to treat axillary and palmar hyperhidrosis by acting on the vegetative nervous system,treat postherpetic neuralgia through its analgesic effect,treat keloid and scar by inhibiting fibroblast proliferation and collagen synthesis,and to delay deepening of wrinkles by transient skeletal muscle paralysis.The most disadvantage of botulinum toxin type A injection is that it can only result in temporary relief or disappearance of symptoms,and repeated injections are required for their long-term control.A lot of reports have indicated that the effects of botulinum toxin type A injection can be maintained for 12 months at most.

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