Progress in lupus erythematosus tumidus
- Author:
- No author available
- Journal Title:
- International Journal of Dermatology and Venereology
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1673-4173.2015.04.005
- Key Word:
- 肿胀性红斑狼疮;光敏感;直接免疫荧光;组织病理;Lupus erythematosus tumidus;Photosensitivity;Direct immunofluorescence;Histopathology
Abstract： Lupus erythematosus tumidus (LET),a subtype of cutaneous lupus erythematosus,is clinically characterized by purple patches and single or multiple exudative plaques with smooth surfaces and sharp boundaries which usually occur on sun-exposed areas,and marked photosensitivity without scar formation or epidermal changes such as erosion,atrophy,scaling and follicular plugging.Histopathologically,LET is characterized by lymphocytic infiltration around deep or superficial blood vessels and appendages as well as by mucin deposition in the reticular dermis without obvious epidermal involvement.Direct immunofluorescence (DIF) staining for immunoglobulins is negative.Chloroquine and hydroxychloroquine are effective for the treatment of LET.
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