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Intravenous immunoglobulin for the treatment of some dermatoses

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Author:
No author available
Journal Title:
International Journal of Dermatology and Venereology
Issue:
2
DOI:
10.3760/cma.j.issn.1673-4173.2015.02.008
Key Word:
皮肤疾病;免疫球蛋白类;注射;治疗应用;Skin diseases;Immunoglobulins;Injections;Therapeutic uses

Abstract: Intravenous immunoglobulin (IVIG) was initially approved as an alternative to antibodies in the treatment of primary immunodeficiency diseases.With further insights into its action mechanism,IVIG has been successfully applied to the treatment of bullous dermatoses,connective tissue diseases,severe drug eruptions,Kawasaki disease,etc.It has been proved that IVIG has good therapeutic effect and increases the survival of patients.Although IVIG is relatively safe and well tolerable,it has some adverse effects.Currently,lack of large-scale randomized controlled trials (RCTs) remains the biggest problem.

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