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Roles of microorganisms in the pathogenesis of rosacea

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Author:
No author available
Journal Title:
International Journal of Dermatology and Venereology
Issue:
1
DOI:
10.3760/cma.j.issn.1673-4173.2014.01.007
Key Word:
痤疮,红斑;发病机制;微生物学;螨;Rosacea;Pathogenesis;Microbiology;Mites

Abstract: Rosacea is a common chronic inflammatory skin disease that predominantly affects the central regions of the face.Its pathogenesis remains unknown,and microorganisms are considered to play an important role in its development.Demodex mites contribute a lot to the development of rosacea,probably through type Ⅳ immunological reaction.Bacillus olemnius and Staphylococcus epidermidis,which are found to be carried by Demodex mites,may synergistically collaborate with Demodex mites in the pathogenesis of rosacea.Besides,Helicobacter pylod and small intestinal bacterial overgrowth may be involved in the initiation of rosacea complicated by digestive tract symptoms,but the correlation and mechanisms remain unclear.There has been no evidence for the correlation between rosacea and Propionibactedum acnes or Wolbachia.

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