Abstract: Vitiligo is a pigmentary disorder characterized by cutaneous or mucous hypopigmentation.It is usually acquired,and may occur at any age,but is more common in young adults.In some patients with vitiligo,the condition gets worse at late spring and early summer,but better in winter.It may affect any body sites with a predilection for exposed sites.Vitiligo can bring psychical and mental stress to patients by affecting their appearance,however,it still remains difficult to treat.At present,commonly used phototherapy for vitiligo includes 308-nm excimer laser,narrow band-ultraviolet B,helium neon laser,etc.Clinical practice has suggested that the efficacy of phototherapy is associated with the type,site,clinical course of vitiligo,as well as treatment sessions,skin types and erythema reaction of patients.