Dendritic cell-specific ICAM-3-grabbing non-integrin in dermatoses and venereal diseases
- Author:
- No author available
- Journal Title:
- International Journal of Dermatology and Venereology
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1673-4173.2013.01.015
- Key Word:
- 皮肤疾病;性传播疾病;树突细胞;DC-SIGN;Skin diseases;Sexually transmitted diseases;Dendritic cells;DC-SIGN
Abstract： Dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN) is a group of C-type lectin receptors specifically expressed on dendritic cells,which can recognize and capture many kinds of glycosylated antigens,and exert immunomodulatory effect through interaction with different carbohydrate ligands and pathogens.As the receptor of a broad-spectrum of pathogens,DC-SIGN is correlated with many pathogens such as virus,bacteria,fungi,and is involved in chronic inflammation and allergic reactions.Recently,more and more attention has been given to the roles of DC-SIGN in dermatoses and venereal diseases.DC-SIGN is mainly distributed on immature DCs in peripheral tissue and mature DCs in lymph tissues,and has also been observed on both keratinocytcs and Schwann cells recently.
- [1]Nobuo, Kanazawa,Naoya, Mikita,Hong-Jin, Li,etc.[Genetic involvement of bacterial sensor molecules in Japanese leprosy].[J].2009,78(3).
- [2]da Silva RC,Segat L,Crovella S.Role of DC-SIGN and L-SIGN receptors in HIV-1 vertical transmission.[J].2011,72(4).
- [3]Liu PT,Phan J,Tang D,etc.CD209+ Macrophages Mediate Host Defense against Propionibacterium acnes.[J].2008,180(7).
- [4]Swaminathan S,Alagarasu K,Harishankar M,etc.CD209 gene polymorphisms in South Indian HIV and HIV-TB patients[J].2009,9(2).
- [5].Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell-induced T helper responses.[J].2009,5(10).
- [6]Fuentes Duculan J,Suarez Farinas M,Zaba LC,etc.A subpopulation of CD163-positive macrophages is classically activated in psoriasis.[J].2010,130(10).
- [7]Uronen-Hansson H,Engering A,Callard R,etc.Neisseria meningitidis expressing lgtB lipopolysaccharide targets DC-SIGN and modulates dendritic cell function[J].2006,8(2).
- [8]Abendroth A,Slobedman E,Huch JH,etc.Impact of varicella-zoster virus on dendritic cell subsets in human skin during natural infection.[J].2010,84(8).
- [9]Geijtenbeek TB,Appelmelk B,Kooyk Y.A fatal attraction: Mycobacterium tuberculosis and HIV-1 target DC-SIGN to escape immune surveillance.[J].2003,9(4).
- [10]Brown GD,Willment JA.C-type lectin receptors in antifungal immunity[J].2008,16(1).
- [11]Modlin RL,Teles RM,Ochoa MT,etc.Interleukin-4 regulates the expression of CD209 and subsequent uptake of Mycobacterium leprae by Schwann cells in human leprosy.[J].2010,78(11).
- [12]Nobile, Cinzia,Petit, Caroline,Moris, Arnaud,etc.Covert Human Immunodeficiency Virus Replication in Dendritic Cells and in DC-SIGN-Expressing Cells Promotes Long-Term Transmission to Lymphocytes.[J].2005,79(9).
- [13]Furmonaviciene R,Ghaemmaghami AM,Boyd SE,etc.The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: experimental analysis of in silico substrate identification and implications in allergic responses.[J].2007,37(2).
- [14]T B, Geijtenbeek,R, Torensma,S J, van Vliet,etc.Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses.[J].2000,100(5).
- [15]Higaki M,Higaki Y,Kawashima M.Increased expression of CD208 (DC-LAMP) in epidermal keratinocytes of psoriatic lesions.[J].2009,36(3).
- [16]Barreiro LB,Quach H,Krahenbuhl J,etc.DC-SIGN interacts with Mycobacterium leprae but sequence variation in this lectin is not associated with leprosy in the Pakistani population.[J].2006,67(1/2).
- [17]Wen ting L,Chen Z,Qing S,etc.Significance of DC-LAMP and DC-SIGN expression in psoriasis vulgaris lesions.[J].2011,91(1).
- [18]de Jong MAWP,de Witte L,Bolmstedt A,etc.Dendritic cells mediate herpes simplex virus infection and transmission through the C-type lectin DC-SIGN[J].2008,89(10).
- [19]Hijazi, Karolin,Wang, Yufei,Scala, Carlo,etc.DC-SIGN Increases the Affinity of HIV-1 Envelope Glycoprotein Interaction with CD4.[J].2011,6(12).