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Association between dermatophyte infections and allergic diseases

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Author:
No author available
Journal Title:
International Journal of Dermatology and Venereology
Issue:
4
DOI:
10.3760/cma.j.issn.1673-4173.2012.04.020
Key Word:
表皮癣菌属;感染;变态反应和免疫学;Epidermophyton;Infection;Allergy and immunology

Abstract: Allergic diseases are common conditions with complex etiological factors.Dermatophytes are important pathogenic fungi as well as common allergens.As several reports have indicated,oral antifungal therapy is effective for the management of allergic diseases.It has been demonstrated that there is a strong association between dermatophytosis and allergic diseases,and the exposure to dermatophyte antigens may induce the production of IgE antibody and result in allergic symptoms in predisposed individuals.This review mainly presents sensitizing mechanism of dermatophytes,dermatophyte antigens,and treatment of allergic diseases complicated by dermatophytosis with a focus on the association between dermatophytosis and allergic diseases,which may provide new ideas for researches into the etiology,pathogenesis,and treatment of some allergic diseases.

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