Abstract: As a new type of topical immunosuppressive agent,pimecrolimus is mainly used in the treatment of atopic dermatitis.Recently,the application range of pimecrolimus has been broadened and it has been widely used in many allergic dermatoses,such as atopic dermatitis,eczema,contact dermatitis,perioral dermatitis,et al.Several clinical studies have suggested that topical pimecrolimus twice daily has favorable effect with few side effects.Therefore,pimecrolimus may have a promising future in the treatment of allergic dermatoses such as dermatitis and eczema.