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Lymphoma-associated cutaneous granulomas

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Author:
No author available
Journal Title:
INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
Issue:
4
DOI:
10.3760/cma.j.issn.1673-4173.2008.04.018
Key Word:
皮肤;肉芽肿;淋巴瘤;Skin;Granuloma;Lymphoma

Abstract: Granuloma formation has been observed as an incidental histopathological phenomenon in several lymphoproliferative disorders.The patterns of cutaneous granulomas associated with lymphomas are classified into two types.The first type is characterized by granulomatous infiltrates admixed with neoplastic cells within specific skin lesions of lymphomas,such as granulomatous mycosis fungoides and granulomatous slack skin.The second type refers to unspecific granulomatous skin lesions commonly seen in systemic iymphomas.Histopathologically,these granulomas can be sarcoid-like,granuloma annulare-like,tuberculoid,and so on.The pathogenesis and prognostic significance of cutaneous granuloma need to be clarified.Granulomas can result in specific manifestations,and obscure the nature of lymphomas,hence,cautions should be given to clinical and histological diagnosis of cutaneous granulomas.

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