Paper - WANFANG MED ONLINE

You Position: Home > Paper

Psoriasis and the Regulation Network of Immune Molecules

( views:211, downloads:46 )

Author:: No author available

Journal Title:: INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY

Issue:: 1

DOI:: 10.3760/cma.j.issn.1673-4173.2006.01.010

Key Word:: 银屑病;免疫;T淋巴细胞

Abstract：银屑病是一常见的免疫性、炎症性慢性皮肤病.在T细胞亚群失衡、角质形成细胞异常增殖活化及最终淋巴细胞在皮损局部的浸润这一过程中,免疫分子以网络的形式参与其中,它们表达异常并相互作用导致免疫调控网络失衡.通过调控网络这一形式,相互诱导、调节、拮抗、相加或协同,调节银屑病免疫应答和炎症反应的发生、发展、转归.

Reference

[1]Akira Kawamura,Kyoichi Adachi,Shunji Ishihara,etc.Correlation between microsatellite instability and metachronous disease recurrence after endoscopic mucosal resection in patients with early stage gastric carcinoma[J].2001,91(2).
[2]Tada Y,Wakugawa M,Tamaki K,etc.Increased serum cutaneous T cell-attracting chemokine (CCL27) levels in patients with atopic dermatitis and psoriasis vulgaris.[J].2003,111(3).
[3]Raychaudhuri SK,Chattedee AD,Raychaudhuri SP,etc.Mast cell density and IL-8 expression in nonlesional and lesional psoriatic skin.[J].2001,40(11).
[4]Boehncke WH,Schon MP,Zollner TM.The molecular basis of lymphocyte recruitment to the skin: clues for pathogenesis and selective therapies of inflammatory disorders.[J].2003,121(5).
[5]Homey B,Lehmann P,Deng G,etc.Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis.[J].2000,164(12).
[6]Frank C, Victor,Alice B, Gottlieb.TNF-alpha and apoptosis: implications for the pathogenesis and treatment of psoriasis.[J].2002,1.
[7]J.‐M. Ovigne,B. S. Baker,D. W. Brown,etc.Epidermal CD8+ T cells in chronic plaque psoriasis are Tc1 cells producing heterogeneous levels of interferon‐gamma[J].2001,10(3).
[8]Kai Singbartl,Jayant Thatte,Michael L. Smith,etc.A CD2-Green Fluorescence Protein-Transgenic Mouse Reveals Very Late Antigen-4-Dependent CD8~+ Lymphocyte Rolling in Inflamed Venules[J].2001,166(12).
[9]Wittmann M,Purwar R,Hartmann C,etc.Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases.[J].2005,124(6).
[10]Ghoreschi K,Rocken M.Immune deviation strategies in the therapy of psoriasis.[J].2004,3(2).
[11]Biedermann T,Prinz J,van Eden W,etc.Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease.[J].2003,9(1).
[12]Kristiansen K,Westergaard M,Flindt E,etc.Inverse Regulation of the Nuclear Factor-kappaB Binding to the p53 and Interleukin-8 kappaB Response Elements in Lesional Psoriatic Skin.[J].2005,124(6).
[13]Deleuran M,Iversen L,Vestergaard C,etc.Tumor necrosis factor-alpha-induced CTACK/CCL27 (cutaneous T-cell-attracting chemokine) production in keratinocytes is controlled by nuclear factor kappaB.[J].2005,29(2).
[14]Duan, H.,Koga, T.,Kohda, F.,etc.Interleukin-8-positive neutrophils in psoriasis[J].2001,26(2).
[15]Hafezi-Moghadam A,Ley K,Thomas KL,etc.L-selectin shedding regulates leukocyte recruitment.[J].2001,193(7).
[16]Andrea, Szegedi,Magdolna, Aleksza,Andrea, Gonda,etc.Elevated rate of Thelper1 (T(H)1) lymphocytes and serum IFN-gamma levels in psoriatic patients.[J].2003,86.
[17]Scarponi C,Girolomoni G,Albanesi C,etc.Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes.[J].2000,115(1).
[18]Bozza M,Bliss JL,Dorner AJ,etc.Interleukin-11 modulates Th1/Th2 cytokine production from activated CD4+ T cells.[J].2001,21(1).
[19]Docke WD,Henze M,Sterry W,etc.Flow cytometric characterization of lesional T cells in psoriasis: intracellular cytokine and surface antigen expression indicates an activated, memory/effector type 1 immunophenotype.[J].2000,292(10).
[20]Walters IB,Bliss JL,Dorner AJ,etc.Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions.[J].1999,104(11).