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氧化损伤与皮肤疾病
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- Author:
- No author available
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1673-4173.2004.02.005
- Key Word:
- 氧化损伤;紫外线;皮肤疾病
Abstract： 人皮肤承受着来自以紫外线为主的多种污染物产生的氧化压力.人皮肤除了具有完善的抗氧化防御系统拮抗外界氧化压力外,机体还可产生一系列针对蛋白质、脂质体及DNA损伤的修复酶.但即使如此,氧化损伤依然存在.氧化损伤主要是由于皮肤中氧化压力与抗氧化防御系统的失衡所致.氧化损伤使机体受损而处于各种病理状态,其与皮肤肿瘤、光老化、多形性日光疹、红斑狼疮、白癜风及银屑病等多种皮肤疾病的发生有一定的相关性.
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