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中毒性表皮坏死松解症研究进展
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- Author:
- No author available
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1673-4173.2003.05.012
- Key Word:
- 表皮坏死松解症,中毒性;细胞凋亡;丙种球蛋白类
Abstract： 中毒性表皮坏死松解症是一种严重威胁生命的疾病,常由药物诱发,现已经证实角质形成细胞凋亡是其最突出的组织学表现,由FasL-Fas介导的细胞免疫反应在中毒性表皮坏死松解症中起到了重要的作用.静脉注射用丙种球蛋白对该病有明显的治疗效果.
- [1]Cassano P,Stella M,Clemente A,etc.Toxic epidermal necrolysis treated with intravenous high-dose immunoglobulins: our experience.[J].2001,203(1).
- [2]P H, Krammer.CD95's deadly mission in the immune system.[J].2000,407(6805).
- [3]Wolkenstein, Pierre,Latarjet, Jacques,Roujeau, Jean-Claude,etc.Randomised comparison of thalidomide versus placebo in toxic epidermal necrolysis.[J].1998,352(9140).
- [4]I, Viard,P, Wehrli,R, Bullani,etc.Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.[J].1998,282(5388).
- [5]Osvaldo, Correia,Luis, Delgado,Jean-Claude, Roujeau,etc.Soluble interleukin 2 receptor and interleukin 1alpha in toxic epidermal necrolysis: a comparative analysis of serum and blister fluid samples.[J].2002,138(1).
- [6]Peter O. Fritsch,Alexis Sidoroff.Drug-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis[J].2000,1(6).
- [7]S, Magina,C, Lisboa,E, Gon?alves,etc.A case of toxic epidermal necrolysis treated with intravenous immunoglobin.[J].2000,142(1).
- [8]Nassif A,Mami Chouaib F,Bachot N,etc.Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis.[J].2002,118(4).
- [9]L E, French,J, Tschopp.Fas-mediated cell death in toxic epidermal necrolysis and graft-versus-host disease: potential for therapeutic inhibition.[J].2000,130(44).
- [10]A.S. Kalgutkar,D.K. Dalvie,J.P. O'Donnell,etc.On the Diversity of Oxidative Bioactivation Reactions on Nitrogen- Containing Xenobiotics.[J].2002,3(4).
- [11]Damas P,Jacob E,Pierard GE,etc.Treatment of drug-induced toxic epidermal necrolysis (Lyell's syndrome) with intravenous human immunoglobulins.[J].2001,27(6).
- [12]P S, Friedmann,I, Strickland,M, Pirmohamed,etc.Investigation of mechanisms in toxic epidermal necrolysis induced by carbamazepine.[J].1994,130(5).
- [13]Correia O,Delgado L,Barbosa IL,etc.CD8+ lymphocytes in the blister fluid of severe acute cutaneous graft-versus-host disease: further similarities with toxic epidermal necrolysis.[J].2001,203(3).
- [14]C. PAUL,P. WOLKENSTEIN,H. ADLE,etc.Apoptosis as a mechanism of keratinocyte death in toxic epidermal necrolysis[J].1996,134(4).
- [15]Lee,Jang,Lee,etc.Fas ligand is expressed in normal skin and in some cutaneous malignancies[J].1998,139(2).
- [16]D A, Hess,M J, Rieder.The role of reactive drug metabolites in immune-mediated adverse drug reactions.[J].1997,31(11).