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白介素12与特应性皮炎
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- Author:
- No author available
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1673-4173.2003.03.014
- Key Word:
- 白介素12;皮炎,特应性
Abstract： 白介素12及其受体都是由两条不同的多肽链构成的异二聚体分子.它们具有多种功能.动物研究显示:白介素12可能是炎症性皮肤病关键的细胞因子,而其受体则可能在特应性皮炎治疗中有一定疗效.白介素12在特应性皮炎中的抗炎作用可能是通过诱导干扰素γ,调节Th1/Th2的平衡及抑制IgE等的产生来实现的.
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