Research progress on cancer-related fatigue

( views:259, downloads:0 )
ZHANG Xue(Department of Medical Oncology,Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China)
Journal Title:
Cancer Research and Clinic
Volume 24, Issue 08, 2012
Key Word:
Neoplasms; Mental fatigue; Pathogenesis; Evaluation; Treatment

Abstract: Fatigue is one of the most common complaints in cancer patients that profoundly affects all aspects of quality of life.However,cancer-related fatigue remains under recognized and poorly treated.This rcview has been conducted with the causes and potential treatments of fatigue in cancer patients.The methods for evaluating fatigue,and possible therapeutic options are also discussed.

  • [1]Stone P,Richards M,A’Hern R,et al.Fatigue in patients with cancers of the breast or prostate undergoing radical radiotherapy.J Pain Symptom Manage,2001,22:1007-1015.
  • [2]Stone P,Hardy J,Broadley K,et al.Fatigue in advanced cancer:a prospective controlled cross-sectional study.Br J Cancer,1999,79:1479-1486.
  • [3]Bower JE,Ganz PA,Desmond KA,et al.Fatigue in long-term breast carcinoma survivors.Cancer,2006,106:751-758.
  • [4]Mock V,Atkinson A,Barsevick A,et al.NCCN practice guidelines for cancerrelated fatigue.Oncol (Williston Park),2000,14:151-161.
  • [5]NCCN Clinical Practice Guidelines in Oncology.Cancer Related Fatigue.
  • [6]Radbruch L,Strasser F,Elsner F,et al.Fatigue in palliative care patients-an EAPC approach.Palliat Med,2008,22:13-32.
  • [7]钱勇,潘跃银,孙国平,等.食管癌新辅助化疗患者生活质量的定量研究.肿瘤研究与临床,2006,18:233-236.
  • [8]Clcarc AJ.The neuroendocrinology of chronic fatigue syndrome.Endoer Rev,2003,24:236-252.
  • [9]何捷,周毅癌症患者抑郁治疗的临床研究.肿瘤研究与临床,2005(增刊):39.
  • [10]Boesen EH,Ross L,Frederiksen K,et al.Psychoeducational intervention for patients with cutaneous malignant melanoma:a replication study.J Clin Oncol,2005,23:1270-1277.
  • [11]Trijsburg RW,van Knippenberg FC,Rijpma SE.Effects of psychological treatment on cancer patients:a critical review.Psychosom Med,1992,54:489-517.
  • [12]Luebbert K,Dahme B,Hasenbring M.The effectiveness of relaxation training in reducing treatment-related symptoms and improving emotional adjustment in acute non-surgical cancer treatment:a metaanalytical review.Psychooncology,2001,10:490-502.
  • [13]Segal R,Evans W,Johnson D,et al.Structured exercise improves physical functioning in women with stages Ⅰ and Ⅱ breast cancer:results of a randomized controlled trial.J Clin Oncol,2001,19:657-665.
  • [14]Kuchinski AM,Reading M,Lash AA.Treatment-related fatigue and exercise in patients with cancer:a systematic review.Medsurg Nurs,2009,18:174-180.
  • [15]Vickers AJ,Straus DJ,Fearon B,et al.Acupuncture for postchemotherapy fatigue:a phase Ⅱ study.J Clin Oncol,2004,22:1731-1735.
  • [16]Lower EE,Fleishman S,Cooper A,et al.Efficacy of dexmethylphenidate for the treatment of fatigue after cancer chemotherapy:a randomized clinical trial.J Pain Symptom Manage,2009,38:650-662.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615