Research progress of Twist gene in breast cancer

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Author:
LI Yan(Department of General Surgery,2nd Affiliated Hospital,Harbin Medical University,Harbin 150086,China)
Journal Title:
Cancer Research and Clinic
Issue:
Volume 24, Issue 08, 2012
DOI:
10.3760/cma.j.issn.1006-9801.2012.08.024
Key Word:
Breast cancer; Twist gene; Neoplasm metastasis

Abstract: There are multiple genes involved in the progress of evolution in breast cancer.Recent study showed that Twist gene may play key role in promoting tumor growth,invasion and metastasis through the epithelial-mesenchymal transition (EMT).Other studies also demonstrated that Twist gene expression maybe associated with patient outcomes and guiding clinical tailored therapies.

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