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Research progress of internal mammary lymph node in breast cancer

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Author:
No author available
Journal Title:
Cancer Research and Clinic
Issue:
12
DOI:
10.3760/cma.j.issn.1006-9801.2011.12.001
Key Word:
内乳区淋巴结;乳腺肿瘤;前哨淋巴结活组织检查;Internal mammary lymph node;Breast neoplasms;Sentinel lymph node biopsy

Abstract: The metastases status of internal mammary lymph node (IMLN) is an independent prognostic factor for breast cancer and it also is an important reference for neoplasm staging.The patients with IMLN metastases consistently have worse outcomes.The overall risk of IMLN metastases is 18 %-33 %.Metastases exclusively situated in the IMLN,without concurrent axillary metastases,occur in 2 %-11% of patients.Factors related to IMLN metastases include the status of axillary node,the age of patients,the localization and characteristics of primary tumor.Recently,with the development of sentinel lymph node biopsy (SLNB), internal mammary-SLNB may access the status of IMLN with a minimal risk. Internal mammary-SLNB procedure can improve the system for nodal staging of breast cancer,and it will contribute to the individualized treatment for breast cancer patients.

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