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Clinical research on prediction marker of efficacy in advanced non-small cell lung cancer

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Author:
No author available
Journal Title:
CANCER RESEARCH AND CLINIC
Issue:
9
DOI:
10.3760/cma.j.issn.1006-9801.2010.09.002
Key Word:
癌,非小细胞肺;靶向治疗;生物学标志;Carcinoma,non-small-cell lung;Target therapy;Biological marker

Abstract: Individualized therapy is the current trend of treatment in advanced non-small cell lung cancer, the key of individualized therapy is to administrer different treatment options through different biological markers or clinical markers. Currently, biological markers include EGFR protein expression, EGFR mutations, EGFR gene copy, k-ras mutation, EML4-ALK gene fusion, C-MET gene. Clinical markers include rash, pathological types, etc. This article will give a review about those biomarkers.

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