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Molecular marker makes tailored target therapy for mCRC treatment

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Author:
No author available
Journal Title:
CANCER RESEARCH AND CLINIC
Issue:
8
DOI:
10.3760/cma.j.issn.1006-9801.2008.08.002
Key Word:
结直肠肿瘤;肿瘤转移;靶向治疗;Colorectal neoplasms;Neoplasm metastasis;Targeted therapy

Abstract: The latest advances on target therapies of cancer were presented on the 44th Annual Meeting of American Society of Clinical Oncology(ASCO)in 2008.One of the most important results was the outstanding efficacy of Cetuximab in Metastatic Colorectal Cancer fIncao patients with k-ras"wild-type".Besides,detection of k-ras statuswouldmakeitpossibleforthetailoredtargettherapy of mCRC.Itwasestimatedthat k-ras gene status would become a predictive molecular marker for Cetuximab treatment in mCRC.

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