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Prognostic significance of primary tumor size in gastrointestinal stromal tumor
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- Author:
- No author available
- Journal Title:
- CANCER RESEARCH AND CLINIC
- Issue:
- 8
- DOI:
- 10.3760/cma.j.issn.1006-9801.2006.08.005
- Key Word:
- 胃肠间质瘤;预后
Abstract： 目的 探讨胃肠道间质瘤(GIST)原发肿瘤大小与预后的关系.方法 对该院1990年1月至2006年3月132例能完全切除的GIST患者的临床资料和病理切片(含免疫组织化学检查)重新复核并进行随访,分析原发肿瘤大小与预后的关系.结果 患者中位生存时间为66.0个月,术后2年和5年生存率分别为89.4%和70.9%.原发灶肿瘤完全切除术患者的生存率与其性别、肿瘤部位和大小、肿瘤性质、核分裂及复发转移有关;但多因素的Cox回归分析显示,术后生存率仅与肿瘤大小、肿瘤性质和复发转移相关(P＜0.05).以2 cm为界比较生存率有统计学意义(P＜0.05),以5 cm为界比较生存率无统计学意义(P＞0.05).结论 GIST仍以外科治疗为主,GIST原发灶大小是影响预后的独立高危因素,直径≥2 cm的患者应加强随诊.
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