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CLINICAL RESEARCH ON THE VARIANCE OF BONE MINERAL DENSITY AND BONE METABOLISM OF CARCINOMA PATIENTS WITH BONE MATASTASIS
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- Author:
- No author available
- Journal Title:
- CANCER RESEARCH AND CLINIC
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1006-9801.2003.01.006
- Key Word:
- 骨转移瘤;骨密度;骨钙素;I型胶原羧基末端肽
Abstract： 目的:研究骨转移瘤患者骨密度和骨代谢状态的变化.方法:采用双能X线骨密度仪(DEXA)测量20例骨转移瘤患者骨密度(BMD),同时采用放射免疫法测定血清骨钙素(BGP),I型胶原羧基末端肽(ICTP)水平,并与20例正常人作对照.结果:骨转移瘤组L2、L 3、L4,右股骨颈,右Ward区和右大转子BMD显著下降(P＜0.05～P＜0.001).骨转移瘤组血清BGP、ICTP显著升高(P＜0.05～P＜0.001).结论:骨转移瘤患者腰椎、髋部BMD下降,血清BGP、ICTP升高,骨转换增快.
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