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EPOR EXPRESSION RELATED TO TUMOR INVASION IN HUMAN BREAST CANCER
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- Author:
- No author available
- Journal Title:
- CANCER RESEARCH AND CLINIC
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1006-9801.2003.01.003
- Key Word:
- 乳腺癌;EpoR;肿瘤诊断
Abstract： 目的:检测乳腺癌红细胞生成素受体(EpoR)的表达与乳腺癌浸润性的关系.方法:用Western印迹法检测46例乳腺癌组织及其相邻非癌组织的EpoR的表达,探讨其表达与浸润性的关系.结果:60.9%(28/46)乳腺癌组织EpoR表达阳性,其相邻非癌组织的EpoR的表达率为17.4%(8/46).32例(78.2%)浸润性乳腺癌组织中25例表达EpoR,14例(21.4%)非浸润性乳腺癌组织中3例表达EpoR;EpoR阳性表达与其浸润性具有明显的相关性,P＜0.05.结论:乳腺癌组织可有EpoR的表达;EpoR的表达与乳腺癌浸润性密切相关.
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