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CONSTRUCTING A HIGH METASTASIS SUBLINE FROM LOVO CELL AND STUDYING ITS BIOLOGICAL CHARACTERISTICS
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- Author:
- No author available
- Journal Title:
- CANCER RESEARCH AND CLINIC
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1006-9801.2002.02.004
- Key Word:
- Lovo细胞;亚系;电泳;DNA含量
Abstract： 目的：建立高侵袭Lovo细胞亚系以及研究其生物学特性。方法：应用裸鼠体内连续传代法，筛选并建立高侵袭Lovo细胞亚系，并测量Lovo亚系电泳泳动速率、细胞周期和DNA含量。结果：Lovo亚系细胞电泳泳动速率明显高于其母系Lovo细胞；其增殖周期(S+G2M)百分率为57.4％，高于其母系Lovo细胞的41.7％，且其DNA含量也远高于其母系细胞。结论：Lovo亚系细胞比Lovo母系细胞具有更高侵袭力和更快的增殖能力。
- [1]F, Darro,A, Kruczynski,C, Etievant,etc.Characterization of the differentiation of human colorectal cancer cell lines by means of Voronoi diagrams.[J].1993,14(7).
- [2]S, Aznavoorian,A N, Murphy,W G, Stetler-Stevenson,etc.Molecular aspects of tumor cell invasion and metastasis.[J].1993,71(4).
- [3]Javed Akhter,Xianghai Chen,Patricia Bowrey,etc.Vitamin D<sub>3</sub> analog, EB1089, inhibits growth of subcutaneous xenografts of the human colon cancer cell line, LoVo, in a nude mouse model[J].1997,40(3).
- [4]徐国超,张蕴惠.人牙龈成纤维细胞电泳行为的研究[J].1996,(3).
- [5]Alan Werner,Elizabeth Bender,William Mahaffey,etc.Inhibition of experimental liver metastasis by combined treatment with tamoxifen and interferon[J].1996,7(3).
- [6]高进.癌的侵袭与转移——基础研究与临床[M].1996.