Abstract： Objective To observe the prognosis of visual acuity (VA) of patients with different classification of polypoidal choroidal vasculopathy (PCV).Methods Sixty-seven PCV patients (68 eyes) diagnosed by fundus photography,fundus fluorescein angiography,indocyanine green angiography (ICGA)and ocular coherence tomography were enrolled in this retrospective study.The patients were classified into static,exudative,small hemorrhage and large hemorrhage according to activity and pathological characteristics of lesions.The patients were classified into aciniform,single or several single,combined branching choroidal vascular network (BVN) according to morphological characteristics and combination with BVN of lesions on ICGA.The patients also were classified into macular,vascular arcade,peripapillary and mixing zone according to distribution of lesions.The VA of all the types were observed.Results There were 16,19,19,14 eyes in the type of static,exudative,small hemorrhage and large hemorrhage PCV,which with logMAR VA of 0.34±0.52,0.70±0.98,0.60±0.50,0.91±0.75 respectively.The VA of static PCV patients was better than that in exudative,small hemorrhage and large hemorrhage PCV patients (q=4.75,4.26,5.13; P＜0.05).There was no significant difference of VA between exudative and small hemorrhage PCV patients (q=0.98,P＞0.05).There were 22,38 and eight eyes in the type of aciniform,single or several single,combined BVN PCV,which with logMAR VA of 0.52 ± 0.55,0.59 ± 0.43,0.80±0.95 respectively.The VA of combined BVN PCV patients was worse than that in aciniform and single or several single PCV patients (q＝3.81,3.02 ; P＜0.05 ).There were 34,13,8 and 13 eyes in the type of macular,vascular arcade,peripapillary and mixing zone PCV,which with logMAR VA of 0.78±0.43.0.5±0.37,0.38±0.27,0.74±0.41 respectively.The VA of macular PCV patients was less than that in vascular arcade and peripapillary PCV patients (q=4.61,5.11;P＜0.05).There was no significant difference of VA between macula and mixing zone PCV patients (q=0.73,P＞0.05).Conclusions The VA of PCV patients is variable.It is related to activity and pathological characteristics of lesions,morphological characteristics and combination with BVN of lesions on ICGA,and distribution of lesions.