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Efficacy of vitreoretinal surgery for X-linked retinoschisis and its complications

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Author:
No author available
Journal Title:
Chinese Journal of Ocular Fundus Diseases
Issue:
2
DOI:
10.3760/cma.j.issn.1005-1015.2012.02.002
Key Word:
视网膜劈裂症/先天性;视网膜劈裂症/外科学;玻璃体切除术/方法;治疗结果;Retinoschisis/congenital;Retinoschisis/surgery;Vitrectomy/methods;Treatment outcome

Abstract: Objective To evaluated the efficacy of vitreoretinal surgery for X-linked retinoschisis (XLRS) and its complications.Methods Twenty-one XLRS patients (27 eyes) with retinal detachment or vitreous hemorrhage who were treated by vitreoretinal surgery were enrolled in this study. There were microcystis-like splitting in all the eyes.The mean visual acuity was 0.11 ± 0.09 and the mean area of macular splitting was (1.09±0.56) mm2.Among the eyes,there were 12 eyes with rhegmatogenous retinal detachment,five eye with traction retinal detachment,six eyes with vitreous hemorrhage and four eyes with retinal detachment and vitreous hemorrhage.All the patients underwent a standard three-port pars plana vitrectomy.Internal limiting membrane peeling,laser photocoagulation,and C3F8 gas or silicone oil tamponade were carried out in different condition.The follow-up was 9 - 122 months (average 51 months).The preoperative visual acuity and anatomic structure of retina were observed.Results The mean visual acuity at last visit was increased to 0.26±0.15,the difference was significant (t=-6.320,P=0.000).It improved in 20 eyes (74.1% ),remained unchanged in seven eyes (25.9 %).The retina remained attached in 27 eyes.The mean area of macular splitting was decreased to (0.29 ±0.21) mm2,the difference was significant (t=10.358,P=0.000).The complications were found in four eyes (14.8%) which including two eyes with proliferative vitroretinopathy and traction retinal detachment six and eight months after surgery,one eye with cataract four months after surgery,and one eye with vitreous hemorrhage 15 months after surgery.The retina remained attached in these four eyes after reoperation.Conclusion Vitreoretinal surgery can significantly improve visual acuity,resume the anatomic structure of retina.

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