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Classification of Bruch' s membrane in the choriocapillario-Bruch' s membrane-retinal pigment epithelium complex in central serous chorioretinopathy by optical coherence tomography

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
Issue:
4
DOI:
10.3760/cma.j.issn.1005-1015.2011.04.005
Key Word:
视网膜疾病/治疗;脉络膜疾病/治疗;色素上皮,眼;Bruch膜;体层摄影术,光学相干;Retinal diseases/therapy;Choroid diseases/ therapy;Pigment epithelium of eye;Bruch membrane;Tomography,optical coherence

Abstract: Objective To observe the types and features of Bruch's membrane (BM) in the choriocapillario-Bruch' s membrane-retinal pigment epithelium complex (CBRP-C) in central serous chorioretinopathy (CSC) by optical coherence tomography (OCT). Methods This is a retrospective case control study. Sixty eyes of 60 patients (43 males, 17 females) with CSC who underwent laser photocoagulation (51 eyes) or half-dose verteporfin photodynamic therapy (9 eyes) were enrolled. The macular area of all the patients was scanned by Spectralis-OCT before and after the treatment, BM was observed as the core indicators of CBRP-C. According to the reflection band, BM was classified into distinguishable BM and indistinguishable BM. The distinguishable BM was classified into phenotype BM (with a sub-RPE fluid cavity) and cryptotype BM (without a sub-RPE fluid cavity). The types and features of BM in CBRP-C of CSC patients before and after the treatment were comparatively analyzed. Results Before the treatment, distinguishable BM were observed in all patients, including 59 eyes (98.3%) with phenotype BM and 1 eye (1.7%) with cryptotype BM. At 1 month after laser photocoagulation, there were, 1/51 eye (2.0%) with indistinguishable BM, and 50/51 eyes (98.0%) with distinguishable BM,including 34 eyes (68.0%) with phenotype BM and 16 eyes (32.0%) with cryptotype BM. At 1 month after half-dose PDT, there were 1/9 eye (11.1%) with indistinguishable BM and 8/9 eyes (88.9%) with distinguishable BM, including 1 eye (12.5%) with phenotype BM and 7 eyes (87.5%) with cryptotype BM. Conclusion The phenotype BM exists in CSC patients before and after the treatment, but it has been improved after treatment.

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