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Morphologic changes of central serous chorioretinopathy evaluated by Fourier-domain optical coherence tomography

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
Issue:
3
DOI:
10.3760/cma.j.issn.1005-1015.2009.03.003
Key Word:
脉络膜视网膜炎/诊断;体层摄影术,光学相干;荧光素血管造影术;色素上皮,眼;诊断显像;Chorioretinitis/diagnosis;Tomography,optical coherence;Fluorescein angiography;Pigment epithelium of eye;Diagnostic imaging

Abstract: Objective To evaluate the morphological changes of retinal neuroepithelium of central serous chorioretinopathy (CSC) by Fourier-domain optical coherence tomography(FD-OCT). Methods FD-OCT scan was performed on 92 eyes of 88 patients with CSC. The CSC diagnosis was established by international visual acuity chart, slit-lamp microscope, direct/indirect ophthalmoscope, fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA). 6 mm horizontal line OCT scan was performed utilizing the infrared light emitted by diode, the scan depth was 2 mm with a 6 mm × 6 mmtransverse area. The vertical and horizontal resolution was 5 μm and 18/.tin respectively. The scan mode was 512× 128. Results The uplift of retinal neuroepithelium, separation or abnormal band of retinal pigment epithelial (RPE) were found in all eyes. There were 83 eyes (90. 22%) of pigment epithelial detachment (PED), 68 eyes (73.91%) of nodular protruding of RPE, 5 eyes (5. 43%) of localized RPE defects in the PED lesion, 36 eyes (39.14%) of dust-like reflects in the subretinal space and 59 eyes (64. 14%) of granular deposits in the subretinal space. Conclusion Fourier-domain OCT scans can detect detailed morphologic changes in the retina of CSC patients.

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