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Experimental tests of ophthalmic drugs and related issues

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
Issue:
6
DOI:
No doi available
Key Word:
药物评价;药物毒性;细胞学;动物实验;Drug evaluation;Drug toxicity;Cytology;Animal experimentation

Abstract: Study of new or previously known drugs for new applications in the treatments of eye diseases hasbeen one of the ma ior subjects in the ophthalmic field.However,we had found several caveats in the recently publishedpapers on experimental ophthalmic drug studies,such as new-drug trials lack of systemic designing,experimentalstudies without following the standard guidelines,in-vivo animal tests bypassed the necessary in-vitro cell screenings,and studies lack known-drug controls,etc.In order to improve the quality of such kind of studies,researchers should befamiliar with the standard procedures of new drug testing,and with the basic rules for drug screenings and efficacyassessments by in-vitro cell culture systems and in-vivo animal models.

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