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Alcohol consumption and the risk of recurrent atrial fibrillation after catheter ablation among Chinese men

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Author:
No author available
Journal Title:
Chinese Journal of Cardiac Arrhythmias
Issue:
4
DOI:
10.3760/cma.j.issn.1007-6638.2012.04.004
Key Word:
心房颤动;射频导管消融;饮酒;Atrial fibrillation;Radiofrequency catheter ablation;Alcohol consumption

Abstract: Objective The aim of this study was to evaluate the association of alcohol consumption with the outcome of AF ablation among Chinese men.Methods The study involved 192 consecutive Chinese men who underwent catheter ablation of AF (64 patients with persistent AF).Participants were categorized as non-drinkers,light or moderate drinkers,and heavy drinkers according to the amount of alcohol intake per week before the ablation.Results After a mean follow-up of ( 17.7±6.1 ) months (5 ~31 months),66 (34.4%) patients had recurrent AF after ablation.Heavy drinkers,found in 29.7% of candidates for AF ablation,had a significantly larger left atrial(LA) size and a higher incidence of recurrent AF after ablation compared to nondrinkers and light or moderate drinkers.In addition,alcohol consumption ( HR=1.765,95% CI 1.298 ~2.400,P<0.001 ),persistent AF (HR=1.64,95% CI 1.006 ~ 2.673,P=0.047 ),type 2 diabetes ( HR =2.409,95% CI 1.332 ~4.385,P=0.004),CHADS2 score≥2 ( HR=2.0,95% CI 1.090 ~3.672,P=0.025),dilated LA ( HR=1.073,95% CI 1.027 ~ 1.120,P=0.002) were significantly associated with AF recurrence after the procedure.Multivariate Cox regression analysis revealed that alcohol consumption ( HR =1.547,95% CI 1.108 -2.161,P=0.010),type 2 diabetes (HR=1.939,95% CI 1.038 ~ 3.622,P=0.038) and LA size ( HR =1.046,95% CI 1.000 ~ 1.095,P=0.050) were independent predictors of recurrent AF after ablation Conclusion Consuming heavier amounts of alcohol was associated with an increased risk of recurrent AF after catheter ablation among Chinese men.Alcohol consumption could independently predict the outcome of AF ablation.

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