Consecutive measurement of cervical length during uncomplicated pregnancy through transvaginal ultrasound

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Author:
CHEN Jun-ya(Department of Obstetrics and Gynecology,Peking University First Hospital, Beijing 100034, China)
FAN Xiao-dong()
CHEN Qian(Department of Obstetrics and Gynecology,Peking University First Hospital, Beijing 100034, China)
SHI Chun-yan(Department of Obstetrics and Gynecology,Peking University First Hospital, Beijing 100034, China)
SUN Wei-jie(Department of Obstetrics and Gynecology,Peking University First Hospital, Beijing 100034, China)
SUN Yu(Department of Obstetrics and Gynecology,Peking University First Hospital, Beijing 100034, China)
FAN Li-xin(Department of Obstetrics and Gynecology,Peking University First Hospital, Beijing 100034, China)
ZHANG Xiao-xiao(Department of Obstetrics and Gynecology,Peking University First Hospital, Beijing 100034, China)
YANG Hui-xia(Department of Obstetrics and Gynecology,Peking University First Hospital, Beijing 100034, China)
Journal Title:
Chinese Journal of Perinatal Medicine
Issue:
Volume 15, Issue 01, 2012
DOI:
10.3760/cma.j.issn.1007-9408.2012.01.005
Key Word:
Pregnancy;Cervical length measurement;Ultrasonography,prenatal

Abstract: Objective To investigate the change of cervical length (CL) during uncomplicated pregnancy by transvaginal ultrasound and its correlated factors. Methods Data of five hundred and ninety-five normal singleton pregnant women who received vaginal ultrasound examination on CL in their 11-13+6gestational weeks ( Ⅰ stage),20-24 gestational weeks ( Ⅱ stage),28-32 gestational weeks (Ⅲ stage) and ≥36 gestational weeks (Ⅳ stage) were collected and retrospectively analyzed.Related factors were recorded at the same time.Repeated measurement data analysis of variance,t-test and Spearman correlation analysis were applied for statistical analysis. Results (1) The mean values of CL at Ⅰ,Ⅱ,Ⅲ and Ⅳ stage were (38.85±3.11) mm,(38.92±4.10) mm,(36.43±4.69) mm and (30.63±6.11) mm,respectively.There were statistical differences between the CL of any two stages (P<0.01),except for that between Ⅰ and Ⅱ stage.The median values of CL change rates were:Ⅱ-Ⅰ stage0.00%; Ⅲ-Ⅰ stage -5.36%; Ⅳ-Ⅰ stage -20.00%.(2) The CL of pregnant women who were older than 35 was longer than that of those younger than 35 at any stage [ Ⅰ stage:(39.36±3.18) mm vs (38.77±3.10) mm;Ⅱ stage:(39.89±4.61) mm vs (38.88±4.00) mm;Ⅲ stage:(37.29±4.79) mm vs (36.31 ±4.67) mm;Ⅳ stage:(32.25± 5.95) mm vs (30.38±6.10) mm],while significant difference was found only at Ⅳ stage (t=-2.56,P=0.01).The CL of multiparas was longer than that of primiparas [ Ⅰ stage:(38.95±2.59) mm vs (38.76±3.14) mm;Ⅱ stage:(39.54±3.62) mm vs (38.82±4.11) mm;Ⅲ stage:(37.37±4.21) mm vs (36.34±4.70) mm;Ⅳ stage:(31.77±6.05) mm vs (30.59±6.11) mm],while there was no statistical significance within any stage ( P> 0.05). Conclusions Cervix shortens gradually after 28 gestational weeks.Sequential measurement of CL during routine ultrasonic inspection might be helpful in predicting preterm labor.

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